Region wählen
Absenden

Applikon BioSep

Skalierbarer Perfusionsprozess für Zellkulturen

Applikon BioSep ist ein einzigartiges Gerät zur Zellretention für den Prozess der kontinuierlichen Zufuhr von frischem Medium und der Entfernung von verbrauchtem Medium bei gleichzeitiger Retention einer hohen Anzahl lebensfähiger Zellen. Es nutzt hochfrequente resonante Ultraschallwellen, um Zellen zu trennen und entfernt so automatisch Zellrückstände, was es zur perfekten Lösung für kontinuierliche Bioprozesse macht.

Für weitere Informationen setzen Sie sich bitte mit uns in Verbindung

Your interest in bioreactor systems

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Argentina

Hixwer 
Phone: +54 11 7078-6666
Email: info@hixwer.com
URL: www.hixwer.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Argentina

Hixwer 
Phone: +54 11 7078-6666
Email: info@hixwer.com
URL: www.hixwer.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Brazil

Sotelab
+55 (21) 3392-3563
www.sotelab.com.br

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Brazil

Sotelab
+55 (21) 3392-3563
www.sotelab.com.br

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Chile, Peru

AP Bioprocess
www.ap-bioprocess.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Chile, Peru

AP Bioprocess
www.ap-bioprocess.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Colombia

Intek Group
Phone: +57 316 3550400 - 749 8437
Email: contacto@intekgroup.com.co
URL: www.intekgroup.com.co

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Colombia

Intek Group
Phone: +57 316 3550400 - 749 8437
Email: contacto@intekgroup.com.co
URL: www.intekgroup.com.co

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Czech Republic

Vekamaf
Phone: +420 284 690 881
URL: www.vekamaf.cz

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Czech Republic

Vekamaf
Phone: +420 284 690 881
URL: www.vekamaf.cz

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Denmark

Holm & Halby
Phone: +454326 9400
Email: info@holm-halby.dk
URL: www.holm-halby.dk

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Denmark

Holm & Halby
Phone: +454326 9400
Email: info@holm-halby.dk
URL: www.holm-halby.dk

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Estonia

Bio Techa
Phone: +372 6597101
Email: info@biotecha.ee
URL: www.biotecha.lt

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Estonia

Bio Techa
Phone: +372 6597101
Email: info@biotecha.ee
URL: www.biotecha.lt

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Hungary

Holimex
Phone: +36 1 391 4400
URL: www.holimex.hu

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Hungary

Holimex
Phone: +36 1 391 4400
URL: www.holimex.hu

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

India

Spinco Biotech Pvt. Ltd.
Phone: +91 44 45678900
Email: info@spincotech.com
URL: www.spincotech.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

India

Spinco Biotech Pvt. Ltd.
Phone: +91 44 45678900
Email: info@spincotech.com
URL: www.spincotech.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Indonesia

PT Arico Sainsindo Nusantara
Phone: +62-21 580 6342 / 3
Email: arico@dnet.net.id
URL: www.ptarico.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Indonesia

PT Arico Sainsindo Nusantara
Phone: +62-21 580 6342 / 3
Email: arico@dnet.net.id
URL: www.ptarico.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Ireland

Asistec
Phone: +353(0)1286 8796
Email: info@asistec.ie
URL: www.asistec.ie

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Ireland

Asistec
Phone: +353(0)1286 8796
Email: info@asistec.ie
URL: www.asistec.ie

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Israel

Medent Group
Phone: +97286237984
Email: info@medent.co.il
URL: medent.co.il

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Israel

Medent Group
Phone: +97286237984
Email: info@medent.co.il
URL: medent.co.il

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Italy

Steroglass
Phone: +39 075 609091
Email: info@steroglass.it 
URL: www.steroglass.it

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Italy

Steroglass
Phone: +39 075 609091
Email: info@steroglass.it 
URL: www.steroglass.it

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Japan

Sanyo Trading Co., LTD
Phone: +81-3-3518-1196
URL: www.sanyo-trading.co.jp

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Japan

Sanyo Trading Co., LTD
Phone: +81-3-3518-1196
URL: www.sanyo-trading.co.jp

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Lithuania

Bio Techa
Phone: +370 5 237 60 07
Email: info@biotecha.lt
URL: www.biotecha.lt

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Lithuania

Bio Techa
Phone: +370 5 237 60 07
Email: info@biotecha.lt
URL: www.biotecha.lt

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Norway

Bio Nordica
Phone: 23 03 58 00
Email: info@bionordika.no
URL: bionordika.no

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Norway

Bio Nordica
Phone: 23 03 58 00
Email: info@bionordika.no
URL: bionordika.no

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Poland

Labo Baza
Phone: +4861 812 57 45
Email: biuro@labobaza.pl
URL: www.labobaza.pl

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Poland

Labo Baza
Phone: +4861 812 57 45
Email: biuro@labobaza.pl
URL: www.labobaza.pl

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Portugal

Aplitech Biolab
Phone: +34 629818802
www.aplitechbiolab.com

 

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Portugal

Aplitech Biolab
Phone: +34 629818802
www.aplitechbiolab.com

 

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Russia

Abtek
Phone: +7(495) 723-64-97
Email: abtek@abtek.ru
URL: abtek.ru

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Russia

Abtek
Phone: +7(495) 723-64-97
Email: abtek@abtek.ru
URL: abtek.ru

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Singapore

Zil Sci Pte. Ltd.
Phone: +65 6767 2929
Email: ENQUIRY@ZILSCI.COM
URL: www.zilsci.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Singapore

Zil Sci Pte. Ltd.
Phone: +65 6767 2929
Email: ENQUIRY@ZILSCI.COM
URL: www.zilsci.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Slovakia

Vekamaf
Phone: +421-2-52932891
URL: www.vekamaf.cz

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Slovakia

Vekamaf
Phone: +421-2-52932891
URL: www.vekamaf.cz

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

South Africa

Seperations
Phone: +27 11 919 1000
Email: info@separations.co.za
URL: separations.co.za

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

South Africa

Seperations
Phone: +27 11 919 1000
Email: info@separations.co.za
URL: separations.co.za

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

South Korea

SeouLin Bioscience
Phone: +821670-5911
Email: support@seoulin.co.kr
URL: www.seoulin.co.kr

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

South Korea

SeouLin Bioscience
Phone: +821670-5911
Email: support@seoulin.co.kr
URL: www.seoulin.co.kr

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Spain

Aplitech Biolab
Phone: +34 629818802
www.aplitechbiolab.com

 

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Spain

Aplitech Biolab
Phone: +34 629818802
www.aplitechbiolab.com

 

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Switzerland

Resea Biotec
Phone: +41 34 531 08 20
Email: office@reseabiotec.ch
URL: www.reseabiotec.ch

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Switzerland

Resea Biotec
Phone: +41 34 531 08 20
Email: office@reseabiotec.ch
URL: www.reseabiotec.ch

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Taiwan

Tseng Hsiang Life Science Ltd.
Phone: +862-27851156
Email: info@thco.com.tw
URL: www.thco.com.tw

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Taiwan

Tseng Hsiang Life Science Ltd.
Phone: +862-27851156
Email: info@thco.com.tw
URL: www.thco.com.tw

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Meditop Co., Ltd

Holm & Halby
Phone: +662 9331133
Email: info@meditopthailand.com
URL: meditopthailand.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Meditop Co., Ltd

Holm & Halby
Phone: +662 9331133
Email: info@meditopthailand.com
URL: meditopthailand.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Turkey

Ant Teknik
Phone: +90 216 422 6700
Email: antteknik@antteknik.com 
URL: www.antteknik.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Turkey

Ant Teknik
Phone: +90 216 422 6700
Email: antteknik@antteknik.com 
URL: www.antteknik.com

The Applikon BioSep 50 liter perfusion device
The Applikon BioSep 10 liter perfusion device
The Applikon BioSep 1 liter perfusion device
Applikon BioSep

Die ideale Lösung für langfristige Kultivierung

  • Automatische Entfernung von Zellrückständen
  • Keine Beschädigung der Zellen
  • Ohne Anwuchs oder Verstopfung, daher für langfristigen Betrieb geeignet
  • Skalierbares Perfusionsgerät (0,1– 1000 l/Tag)

Hohe Abscheideleistung

Der Einsatz der akustischen Resonanztechnologie ermöglicht eine hohe Abscheideleistung (99 %), ohne die Zellen zu beschädigen. Eine Standard-Betriebsart umfasst beispielsweise eine Entnahmepumpe am Auslass der Resonatorkammer und eine Umwälzungspumpe für die Rückführung separierter Zellen, die sich vom akustischen Energiefeld in der Resonanzkammer abgesetzt haben. Alternativ kann das Applikon BioSep-System auch eingesetzt werden, um einen halbkontinuierlichen Betrieb oder alternative Strategien der Zellumwälzung zu ermöglichen.

Einfache Montage und Demontage

Applikon BioSep kann direkt auf die Kopfplatte des Bioreaktors montiert werden. Eine umfassende Charakterisierung hat die volle Skalierbarkeit zwischen den verschiedenen Größen nachgewiesen, sodass Sie direkt zu Beginn Ihrer Prozessoptimierung im Perfusionsmodus starten und diesen bis hin zur Produktion beibehalten können.
Das Applikon BioSep-System ist in den Größen 1 l/Tag, 10 l/Tag, 50 l/Tag, 200 l/Tag und 1000 l/Tag erhältlich und mit Bioreaktoren aller Marken kompatibel.

Unter cGMP-Bedingungen geprüft

Das Applikon BioSep System wird als Perfusionsgerät in verschiedenen kommerziell betriebenen cGMP-Verfahren eingesetzt. Das 50-l/Tag- und das 200-l/Tag-Separationsmodell werden standardmäßig mit allen für den cGMP-Betrieb erforderlichen Dokumentationen und Dienstleistungen geliefert.

Technische Daten

BioSep-System 1 l 10 l 50 l 200 l 1000 l
Maximale Perfusionsrate 1 l/Tag 7 l/Tag 45 l/Tag 200 l/Tag 1000 l/Tag
Minimale Perfusionsrate 0,1 l/Tag    0,7 l/Tag 4,5 l/Tag 20 l/Tag 100 l/Tag
Abscheideleistung Bis zu 99 % (je nach Zellkonzentration und Perfusionsfluss)
Minimale Zellkonzentration 2 × 105 Zellen/ml (je nach Zellgröße)
Bioreaktoranschluss Rohr 6 mm AD Rohr 12 mm AD Separat montiert Separat montiert Separat montiert
Mittlere Zulaufleitung Schlauchtülle 3 mm Schlauchtülle 6 mm Schlauchtülle 10 mm TC 0,5" TC 0,5"
Rücklaufleitung zum Bioreaktor Schlauchtülle 3 mm Tauchrohr 6 mm AD TC 0,5" TC 0,5" TC 0,5"
Perfusionsauslass Schlauchtülle 3 mm Schlauchtülle 6 mm Schlauchtülle 6 mm TC 0,5" TC 0,5"
Gewicht 0,1 kg 0,5 kg 1,5 kg 13 kg 70 kg
Resonatorvolumen 0,7 ml 7 ml 50 ml 290 ml 1450 ml
           
BioSep-Steuerung APS 995 APS 990 APS 990 APS 992 APS 993
Leistung BioSep-Steuerung 15 Watt 150 Watt 150 Watt 350 Watt 1500 Watt
Abmessungen BioSep-Steuerung (T × B × H, mm) In Kombination
mit my-Control
305 × 130 × 130 305 × 130 × 130 450 × 400 × 135 450 × 300 × 135
Gewicht BioSep-Steuerung (kg) In Kombination
mit my-Control
3,5 3,5 17,6 43