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Applikon BioBench

Sterilize-in-Place-Bioreaktor im Tischformat 

Der vielseitige Applikon BioBench imitiert den kommerziellen Maßstab in einer verkleinerten Version auf Ihrem Labortisch, wobei die geometrischen Verhältnisse eines kommerziellen Maßstabs beibehalten werden. Das konsequente Konzept der Modularität, bei dem Standardmodule für den Aufbau des Bioreaktors verwendet werden, vereinfacht die Anpassung an alle spezifischen Anforderungen für die Kultivierung von Mikroorganismen oder höheren Zellen.

Für weitere Informationen setzen Sie sich bitte mit uns in Verbindung

Your interest in bioreactor systems

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Argentina

Hixwer 
Phone: +54 11 7078-6666
Email: info@hixwer.com
URL: www.hixwer.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Argentina

Hixwer 
Phone: +54 11 7078-6666
Email: info@hixwer.com
URL: www.hixwer.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Brazil

Sotelab
+55 (21) 3392-3563
www.sotelab.com.br

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Brazil

Sotelab
+55 (21) 3392-3563
www.sotelab.com.br

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Chile, Peru

AP Bioprocess
www.ap-bioprocess.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Chile, Peru

AP Bioprocess
www.ap-bioprocess.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Colombia

Intek Group
Phone: +57 316 3550400 - 749 8437
Email: contacto@intekgroup.com.co
URL: www.intekgroup.com.co

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Colombia

Intek Group
Phone: +57 316 3550400 - 749 8437
Email: contacto@intekgroup.com.co
URL: www.intekgroup.com.co

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Czech Republic

Vekamaf
Phone: +420 284 690 881
URL: www.vekamaf.cz

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Czech Republic

Vekamaf
Phone: +420 284 690 881
URL: www.vekamaf.cz

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Denmark

Holm & Halby
Phone: +454326 9400
Email: info@holm-halby.dk
URL: www.holm-halby.dk

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Denmark

Holm & Halby
Phone: +454326 9400
Email: info@holm-halby.dk
URL: www.holm-halby.dk

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Estonia

Bio Techa
Phone: +372 6597101
Email: info@biotecha.ee
URL: www.biotecha.lt

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Estonia

Bio Techa
Phone: +372 6597101
Email: info@biotecha.ee
URL: www.biotecha.lt

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Hungary

Holimex
Phone: +36 1 391 4400
URL: www.holimex.hu

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Hungary

Holimex
Phone: +36 1 391 4400
URL: www.holimex.hu

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

India

Spinco Biotech Pvt. Ltd.
Phone: +91 44 45678900
Email: info@spincotech.com
URL: www.spincotech.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

India

Spinco Biotech Pvt. Ltd.
Phone: +91 44 45678900
Email: info@spincotech.com
URL: www.spincotech.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Indonesia

PT Arico Sainsindo Nusantara
Phone: +62-21 580 6342 / 3
Email: arico@dnet.net.id
URL: www.ptarico.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Indonesia

PT Arico Sainsindo Nusantara
Phone: +62-21 580 6342 / 3
Email: arico@dnet.net.id
URL: www.ptarico.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Ireland

Asistec
Phone: +353(0)1286 8796
Email: info@asistec.ie
URL: www.asistec.ie

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Ireland

Asistec
Phone: +353(0)1286 8796
Email: info@asistec.ie
URL: www.asistec.ie

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Israel

Medent Group
Phone: +97286237984
Email: info@medent.co.il
URL: medent.co.il

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Israel

Medent Group
Phone: +97286237984
Email: info@medent.co.il
URL: medent.co.il

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Italy

Steroglass
Phone: +39 075 609091
Email: info@steroglass.it 
URL: www.steroglass.it

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Italy

Steroglass
Phone: +39 075 609091
Email: info@steroglass.it 
URL: www.steroglass.it

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Japan

Sanyo Trading Co., LTD
Phone: +81-3-3518-1196
URL: www.sanyo-trading.co.jp

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Japan

Sanyo Trading Co., LTD
Phone: +81-3-3518-1196
URL: www.sanyo-trading.co.jp

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Lithuania

Bio Techa
Phone: +370 5 237 60 07
Email: info@biotecha.lt
URL: www.biotecha.lt

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Lithuania

Bio Techa
Phone: +370 5 237 60 07
Email: info@biotecha.lt
URL: www.biotecha.lt

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Norway

Bio Nordica
Phone: 23 03 58 00
Email: info@bionordika.no
URL: bionordika.no

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Norway

Bio Nordica
Phone: 23 03 58 00
Email: info@bionordika.no
URL: bionordika.no

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Poland

Labo Baza
Phone: +4861 812 57 45
Email: biuro@labobaza.pl
URL: www.labobaza.pl

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Poland

Labo Baza
Phone: +4861 812 57 45
Email: biuro@labobaza.pl
URL: www.labobaza.pl

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Portugal

Aplitech Biolab
Phone: +34 629818802
www.aplitechbiolab.com

 

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Portugal

Aplitech Biolab
Phone: +34 629818802
www.aplitechbiolab.com

 

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Russia

Abtek
Phone: +7(495) 723-64-97
Email: abtek@abtek.ru
URL: abtek.ru

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Russia

Abtek
Phone: +7(495) 723-64-97
Email: abtek@abtek.ru
URL: abtek.ru

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Singapore

Zil Sci Pte. Ltd.
Phone: +65 6767 2929
Email: ENQUIRY@ZILSCI.COM
URL: www.zilsci.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Singapore

Zil Sci Pte. Ltd.
Phone: +65 6767 2929
Email: ENQUIRY@ZILSCI.COM
URL: www.zilsci.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Slovakia

Vekamaf
Phone: +421-2-52932891
URL: www.vekamaf.cz

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Slovakia

Vekamaf
Phone: +421-2-52932891
URL: www.vekamaf.cz

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

South Africa

Seperations
Phone: +27 11 919 1000
Email: info@separations.co.za
URL: separations.co.za

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

South Africa

Seperations
Phone: +27 11 919 1000
Email: info@separations.co.za
URL: separations.co.za

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

South Korea

SeouLin Bioscience
Phone: +821670-5911
Email: support@seoulin.co.kr
URL: www.seoulin.co.kr

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

South Korea

SeouLin Bioscience
Phone: +821670-5911
Email: support@seoulin.co.kr
URL: www.seoulin.co.kr

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Spain

Aplitech Biolab
Phone: +34 629818802
www.aplitechbiolab.com

 

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Spain

Aplitech Biolab
Phone: +34 629818802
www.aplitechbiolab.com

 

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Switzerland

Resea Biotec
Phone: +41 34 531 08 20
Email: office@reseabiotec.ch
URL: www.reseabiotec.ch

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Switzerland

Resea Biotec
Phone: +41 34 531 08 20
Email: office@reseabiotec.ch
URL: www.reseabiotec.ch

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Taiwan

Tseng Hsiang Life Science Ltd.
Phone: +862-27851156
Email: info@thco.com.tw
URL: www.thco.com.tw

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Taiwan

Tseng Hsiang Life Science Ltd.
Phone: +862-27851156
Email: info@thco.com.tw
URL: www.thco.com.tw

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Meditop Co., Ltd

Holm & Halby
Phone: +662 9331133
Email: info@meditopthailand.com
URL: meditopthailand.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Meditop Co., Ltd

Holm & Halby
Phone: +662 9331133
Email: info@meditopthailand.com
URL: meditopthailand.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Turkey

Ant Teknik
Phone: +90 216 422 6700
Email: antteknik@antteknik.com 
URL: www.antteknik.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Turkey

Ant Teknik
Phone: +90 216 422 6700
Email: antteknik@antteknik.com 
URL: www.antteknik.com

The BioBench 15 liter benchtop stainless steel bioreactor with ez2-Control

Das Zugpferd für Ihre Prozessentwicklung

  • Kompakte Konstruktion reduziert den Platzbedarf
  • cGMP-konformes Design vereinfacht die Validierung
  • Modularer Aufbau ermöglicht einfache Konfiguration entsprechend den Prozessanforderungen
  • Sorgenfreier Betrieb; keine punktierten Beutel, keine Leckage von Schläuchen und Anschlüssen
 

Unverzichtbar für die Entwicklung von Impfstoffen und Medikamenten

Bioreaktoren spielen eine Schlüsselrolle bei der Entwicklung und Produktion lebensrettender Impfstoffe und Medikamente. Dieser komplexe Prozess erfordert hoch optimierte, modernste Systeme. Mit den standardisierten Bioreaktordesigns von Applikon BioBench können Sie das Gefäß mit Standardkomponenten einfach und flexibel an Ihre Bedürfnisse anpassen.

Sehen Sie sich im Video die Bioreaktoren aus Edelstahl an, die in Bioprozessen verwendet werden.

Einfache Validierung

Die BioBench-Serie entspricht den neuesten Standards für hygienische Verarbeitung und erfüllt die cGMP- und GAMP-Anforderungen. Sie kann mit einem umfangreichen Dokumentationspaket geliefert werden, das eine effiziente Validierung unterstützt.

Einfache Bedienung

Edelstahl-Bioreaktoren minimieren das Risiko einer Kontamination, da nicht bei jedem Durchlauf Verbrauchsmaterialien ausgetauscht werden müssen. Darüber hinaus haben diese sterilisierbaren Bioreaktoren magnetisch gekoppelte Rührwerksanschlüsse anstelle herkömmlicher Anschlüsse mit dynamischen Dichtungen (Lippendichtung oder doppelte Gleitringdichtung). Da es keine Verbindung zur äußeren Umgebung gibt, besteht auch kein Kontaminationsrisiko.

Die offene Rahmenkonstruktion ermöglicht einen einfachen Zugang für Wartung und Betrieb.

Einfache Reinigung

Die Applikon Edelstahl-Bioreaktoren bestehen vollständig aus 316L-Edelstahl in Pharmaqualität und haben eine Oberflächengüte von Ra < 0,4 Mikrometer. Die glatte Oberfläche verhindert, dass Biofilme und Ablagerungen an den Innenteilen der Bioreaktoren haften bleiben. Dies vereinfacht die Reinigung erheblich und gibt die Gewissheit, dass die Bioreaktoren immer reproduzierbar und steril sind.

Technische Daten

  Gesamtvolumen (l) Arbeitsvolumen (l) Mindestarbeitsvolumen (l) Seitenverhältnis Gesamtvolumen (H/Ø) Seitenverhältnis Arbeitsvolumen (H/Ø)
15 Liter BioBench 15 12 4 2,2 1,7
20 Liter BioBench 20 17 4 3,0 2,4
30 Liter BioBench 30 22 7 2,0 1,6
Antriebssystem Magnetisch gekoppeltes, oben montiertes Rührwerk für mikrobielle Kulturen sowie für Zellkultursysteme
Maximale Umfangsgeschwindigkeit (tip speed) des Rührorgans (m/s) 5 m/s für mikrobielle Kulturen und 1 m/s für Zellkulturen
Rührertyp Typ Rushton und Marine, mit Außendurchmesser 0,3–0,5 mal (oder x) Behälterdurchmesser
Gasverteiler Poröser Disperger oder L-Disperger
Kopfraumbegasung Sekundäre Gasleitung
Abgase Wassergekühlter Abgaskondensator mit interner Spirale und/oder Doppelmantel
Probenahme Optionales resterilisierbares Probenahmesystem im DN25-Anschluss in der unteren Seitenwand
Entleerung Resterilisierbarer, unterseitig montierter Balgablauf
Zuleitungen Sterilisierbare Zuleitungen (Schiebeventile) und resterilisierbare Anschlüsse für Zuleitungen
pH-Wert Messung: Handelsüblicher 12-mm-pH-Sensor im DN25-Anschluss in der unteren Seitenwand
  Steuerung: über Säurepumpe oder CO2-Gas (Rotameter oder MFC) in Kombination mit Alkalipumpe
DO2 Messung: Polarographischer 12-mm-DO2-Sensor im DN25-Anschluss in der unteren Seitenwand
  Steuerung: über eine Kombination aus N2, Luft, O2 (Rotameter oder MFC) und Rühren, Kaskadenschaltung möglich
Temperatur Messung: Pt-100 Sensor im DN25-Anschluss in der unteren Seitenwand
  Kultivierungskontrolle: Kühl- und Heizmantel über Bioreaktorwand
Schaum Messung: Höhenverstellbarer Schaumsensor auf Leitfähigkeitsbasis
  Steuerung: über Antischaumpumpe
Level Messung: Höhenverstellbarer Füllstandsensor auf Leitfähigkeitsbasis
  Steuerung: Pumpe zum präzisen Hinzufügen oder Entnehmen von Flüssigkeiten