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Applikon BioPilot

适用于小规模生产的原位灭菌生物反应器

多用途 Applikon BioPilot 是迈向生物工艺生产的第一步。BioPilot 对实验室规模的生物反应器进行线性放大,简化了转移到生产规模的过程,从而加快了上市时间。一致性的模块化设计理念,使用标准模块来构建生物反应器,简化了定制过程,可满足微生物和细胞培养的任何特定要求。

请联系我们了解更多信息

若您想了解生物反应器系统

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Argentina

Hixwer 
Phone: +54 11 7078-6666
Email: info@hixwer.com
URL: www.hixwer.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Argentina

Hixwer 
Phone: +54 11 7078-6666
Email: info@hixwer.com
URL: www.hixwer.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Brazil

Sotelab
+55 (21) 3392-3563
www.sotelab.com.br

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Brazil

Sotelab
+55 (21) 3392-3563
www.sotelab.com.br

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Chile, Peru

AP Bioprocess
www.ap-bioprocess.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Chile, Peru

AP Bioprocess
www.ap-bioprocess.com

请随时通过以下电话号码、电子邮件或网站直接联系我们,以获得及时回应。

中国

电话: +862161973999
邮箱: marcom.easternasia@getinge.com
官网地址: www.getinge.com/cn

 

请随时通过以下电话号码、电子邮件或网站直接联系我们,以获得及时回应。

中国

电话: +862161973999
邮箱: marcom.easternasia@getinge.com
官网地址: www.getinge.com/cn

 

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Colombia

Intek Group
Phone: +57 316 3550400 - 749 8437
Email: contacto@intekgroup.com.co
URL: www.intekgroup.com.co

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Colombia

Intek Group
Phone: +57 316 3550400 - 749 8437
Email: contacto@intekgroup.com.co
URL: www.intekgroup.com.co

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Czech Republic

Vekamaf
Phone: +420 284 690 881
URL: www.vekamaf.cz

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Czech Republic

Vekamaf
Phone: +420 284 690 881
URL: www.vekamaf.cz

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Denmark

Holm & Halby
Phone: +454326 9400
Email: info@holm-halby.dk
URL: www.holm-halby.dk

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Denmark

Holm & Halby
Phone: +454326 9400
Email: info@holm-halby.dk
URL: www.holm-halby.dk

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Estonia

Bio Techa
Phone: +372 6597101
Email: info@biotecha.ee
URL: www.biotecha.lt

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Estonia

Bio Techa
Phone: +372 6597101
Email: info@biotecha.ee
URL: www.biotecha.lt

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Hungary

Holimex
Phone: +36 1 391 4400
URL: www.holimex.hu

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Hungary

Holimex
Phone: +36 1 391 4400
URL: www.holimex.hu

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

India

Spinco Biotech Pvt. Ltd.
Phone: +91 44 45678900
Email: info@spincotech.com
URL: www.spincotech.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

India

Spinco Biotech Pvt. Ltd.
Phone: +91 44 45678900
Email: info@spincotech.com
URL: www.spincotech.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Indonesia

PT Arico Sainsindo Nusantara
Phone: +62-21 580 6342 / 3
Email: arico@dnet.net.id
URL: www.ptarico.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Indonesia

PT Arico Sainsindo Nusantara
Phone: +62-21 580 6342 / 3
Email: arico@dnet.net.id
URL: www.ptarico.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Ireland

Asistec
Phone: +353(0)1286 8796
Email: info@asistec.ie
URL: www.asistec.ie

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Ireland

Asistec
Phone: +353(0)1286 8796
Email: info@asistec.ie
URL: www.asistec.ie

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Israel

Medent Group
Phone: +97286237984
Email: info@medent.co.il
URL: medent.co.il

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Israel

Medent Group
Phone: +97286237984
Email: info@medent.co.il
URL: medent.co.il

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Italy

Steroglass
Phone: +39 075 609091
Email: info@steroglass.it 
URL: www.steroglass.it

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Italy

Steroglass
Phone: +39 075 609091
Email: info@steroglass.it 
URL: www.steroglass.it

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Japan

Sanyo Trading Co., LTD
Phone: +81-3-3518-1196
URL: www.sanyo-trading.co.jp

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Japan

Sanyo Trading Co., LTD
Phone: +81-3-3518-1196
URL: www.sanyo-trading.co.jp

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Lithuania

Bio Techa
Phone: +370 5 237 60 07
Email: info@biotecha.lt
URL: www.biotecha.lt

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Lithuania

Bio Techa
Phone: +370 5 237 60 07
Email: info@biotecha.lt
URL: www.biotecha.lt

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Norway

Bio Nordica
Phone: 23 03 58 00
Email: info@bionordika.no
URL: bionordika.no

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Norway

Bio Nordica
Phone: 23 03 58 00
Email: info@bionordika.no
URL: bionordika.no

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Poland

Labo Baza
Phone: +4861 812 57 45
Email: biuro@labobaza.pl
URL: www.labobaza.pl

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Poland

Labo Baza
Phone: +4861 812 57 45
Email: biuro@labobaza.pl
URL: www.labobaza.pl

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Russia

Abtek
Phone: +7(495) 723-64-97
Email: abtek@abtek.ru
URL: abtek.ru

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Russia

Abtek
Phone: +7(495) 723-64-97
Email: abtek@abtek.ru
URL: abtek.ru

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Singapore

Zil Sci Pte. Ltd.
Phone: +65 6767 2929
Email: ENQUIRY@ZILSCI.COM
URL: www.zilsci.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Singapore

Zil Sci Pte. Ltd.
Phone: +65 6767 2929
Email: ENQUIRY@ZILSCI.COM
URL: www.zilsci.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Slovakia

Vekamaf
Phone: +421-2-52932891
URL: www.vekamaf.cz

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Slovakia

Vekamaf
Phone: +421-2-52932891
URL: www.vekamaf.cz

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

South Africa

Seperations
Phone: +27 11 919 1000
Email: info@separations.co.za
URL: separations.co.za

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

South Africa

Seperations
Phone: +27 11 919 1000
Email: info@separations.co.za
URL: separations.co.za

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

South Korea

SeouLin Bioscience
Phone: +821670-5911
Email: support@seoulin.co.kr
URL: www.seoulin.co.kr

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

South Korea

SeouLin Bioscience
Phone: +821670-5911
Email: support@seoulin.co.kr
URL: www.seoulin.co.kr

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Switzerland

Resea Biotec
Phone: +41 34 531 08 20
Email: office@reseabiotec.ch
URL: www.reseabiotec.ch

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Switzerland

Resea Biotec
Phone: +41 34 531 08 20
Email: office@reseabiotec.ch
URL: www.reseabiotec.ch

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Taiwan

Tseng Hsiang Life Science Ltd.
Phone: +862-27851156
Email: info@thco.com.tw
URL: www.thco.com.tw

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Taiwan

Tseng Hsiang Life Science Ltd.
Phone: +862-27851156
Email: info@thco.com.tw
URL: www.thco.com.tw

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Meditop Co., Ltd

Holm & Halby
Phone: +662 9331133
Email: info@meditopthailand.com
URL: meditopthailand.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Meditop Co., Ltd

Holm & Halby
Phone: +662 9331133
Email: info@meditopthailand.com
URL: meditopthailand.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Turkey

Ant Teknik
Phone: +90 216 422 6700
Email: antteknik@antteknik.com 
URL: www.antteknik.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Turkey

Ant Teknik
Phone: +90 216 422 6700
Email: antteknik@antteknik.com 
URL: www.antteknik.com

The BioPilot stainless steel bioreactor system on skid

准确的生产放大模型

  • 采用紧凑型设计,减少所需占地面积
  • 设计符合 cGMP 标准,简化了验证工作
  • 模块化设计可实现轻松配置,满足工艺要求
  • 尽可能地减少人为错误,实现无忧操作
 

疫苗和药物开发的关键要素

在开发和生产救生疫苗和药品的过程中,生物反应器发挥着关键作用。这一复杂过程需要高度优化的先进系统。凭借 Applikon BioPilot 标准化生物反应器设计,我们可以轻松灵活地定制容器,运用标准化组件来满足任何类型的应用需求。

观看视频,了解在生物工艺中使用的不锈钢生物反应器。

易于验证

BioPilot 系列符合现下的卫生处理标准,满足 cGMP 和 GAMP 要求,并可提供支持高效验证的全面文档说明包。

易于操作

生物反应器采用不锈钢材质,每次运行无需更换任何耗材,从而尽可能地降低污染风险。此外,上述原位灭菌生物反应器均采用磁耦合搅拌器连接。该位置采用磁铁建立连接,而搅拌器轴则使用传统连接方式(唇形密封或双端面机械密封)从生物反应器的外部一直延伸到内部。由于与外界没有联系,因此不存在污染风险。

开放式框架结构易于维护和操作。

方便清洁

Applikon 不锈钢生物反应器系列完全采用医药级 316L 不锈钢制成,表面光洁度达到 Ra < 0.4 微米。表面光滑,可确保生物膜和细胞碎片不会粘附在生物反应器内部。这大大简化了清洁程序,同时可以对生物反应器进行可重复的清洗,让您高枕无忧。

规格

  总容量(升) 工作容量(升) 最小工作容量(升) 总容量高径比 工作容量高径比
30 升细胞中试型 (Pilot Cell) 30 20 7 1.5 1.0
60 升细胞中试型 (Pilot Cell) 60 40 10 1.5 1.0
130 升细胞中试型 (Pilot Cell) 130 100 21 1.5 1.0
40 升微生物中试型 (Pilot Microbial) 40 34 9 3.0 2.4
70 升微生物中试型 (Pilot Microbial) 70 50 13 3.0 2.2
140 升微生物中试型 (Pilot Microbial) 140 100 20 3.0 2.2
270 升微生物中试型 (Pilot Microbial) 270 200 40 3.0 2.2
驱动系统 用于微生物培养的磁耦合底部或顶部安装搅拌器和用于细胞培养系统的顶部安装搅拌器
搅拌桨叶叶尖最大速度 (m/s) 3 m/s(微生物培养)和 1 m/s(细胞培养)
桨叶 Rushton 和 marine,外径为罐体直径的 0.3 - 0.5 倍
气体分布器 多孔分布器、L 型分布器或环式分布器
顶部通气 顶部通气气路
排气 水冷式尾气冷凝器,带内螺旋和/或夹套
取样 下侧壁 DN25 端口可选配可重复灭菌取样系统
排水 安装在底部的可重复灭菌波纹管排水管
补料 可灭菌补料阀(推动阀)和可重复灭菌补料口
pH 测量:12 mm 经典 pH 传感器,接入下侧壁 DN25 端口
  控制:通过酸泵或 CO2 气体(流量计或 MFC)与碱泵组合使用
DO2 测量:12 mm 极谱式 DO2 传感器,接入下侧壁 DN25 端口
  控制:通过 N2、空气、O2(流量计或 MFC)和搅拌的组合
温度 测量:Pt-100 传感器,接入下侧壁 DN25 端口
  培养控制:通过生物反应器夹套冷却和加热
泡沫 测量:高度可调的基于电导率的泡沫传感器
  控制:通过消泡泵
液位 测量:高度可调的电阻式液位传感器,或生物反应器结构中的称重传感器
  控制:补料泵或收获泵